Medically reviewed Stephanie Wright, RN, BSN

Patient Education

Why a Wound Will Not Close

An open wound that refuses to close can be worrying. While many wounds close with time, others remain open even with proper care—often because something is interfering with the body’s ability to rebuild skin and seal the surface.

Key idea

Healing can be happening inside even when the surface isn’t closed yet.

Red flag

Problems arise when internal healing stalls and there’s no progress.

What this guide covers

  • Why wounds fail to close
  • Warning signs a wound is stuck
  • Risks of an open wound
  • Home steps that support closure
  • When to seek medical care

Difference Between Healing and Closing

Healing is what’s happening inside the wound: new tissue forms, inflammation decreases, and the body repairs damage. Closing refers to the skin surface sealing over the wound.

Healing (inside)

A deeper wound may look open but show healthy tissue growth underneath. This can be normal— some wounds must heal from the inside out before the surface can close.

Closing (surface)

Closure may be delayed if the wound stays open without improvement—often signaling an underlying issue. Look for internal progress like healthy pink tissue, less drainage, and gradual size reduction.

Causes of Wounds That Won’t Close

Wounds usually fail to close because one or more barriers prevent new skin from forming. These barriers often overlap.

Tissue damage and delayed closure

Healthy tissue is required for a wound to close. When tissue is damaged too deeply or repeatedly, closure slows. Severe tissue loss can create gaps the body struggles to bridge, and scar tissue (less flexible with reduced blood supply) can interfere with edge movement.

  • Significant tissue loss
  • Poor blood supply
  • Repeated reopening from movement or pressure

Infection and wound separation

Infection is a common reason wounds won’t close. Bacteria trigger ongoing inflammation which prevents skin cells from migrating across the surface. Infection can also weaken wound edges, causing separation or reopening.

  • Persistent drainage
  • Redness or warmth
  • Odor
  • Edges pulling apart

Some infections are subtle and not very painful—especially with nerve damage—so lack of closure plus drainage should raise concern.

Moisture imbalance

Wounds heal best in a controlled, slightly moist environment. Too much moisture can damage surrounding skin, while overly dry wounds can stall healing by limiting cell movement. Dry scabs can also act as a physical barrier.

  • Excess moisture: heavy drainage, incontinence exposure, wrong dressings
  • Too dry: hard scabs, rigid tissue, cracking

Using the appropriate dressing helps protect fragile new tissue and supports steady closure.

Signs a Wound Is Stuck Open

Some wounds need more time. Others show clear signs that closure is not progressing.

No change in size over several weeks
Rolled, thickened, pale edges
Ongoing drainage
Surrounding skin breakdown (maceration/redness)
Reopening after partial closure

Risks of an Open Wound

Higher infection risk

Open wounds allow bacteria easier access to deeper tissue. The longer a wound stays open, the higher the chance of infection.

Delayed healing & chronic wounds

Non-closing wounds may become chronic, require ongoing care, and often signal underlying health problems. Drainage, odor, and frequent dressing changes can interfere with daily life.

Scarring & skin breakdown

Open wounds may heal unevenly. Surrounding skin can break down from moisture or pressure, creating a larger problem.

Systemic complications

In severe cases, infection can spread to deeper tissue or the bloodstream. Fever, chills, confusion, or worsening pain may indicate a medical emergency.

Supporting Closure at Home

Daily habits still matter and can support closure alongside medical care.

Care consistency

Follow wound care instructions carefully and keep dressings clean.

Match dressings to drainage

Use dressings appropriate for the exudate level and change them as directed.

Reduce pressure & friction

Protect fragile tissue from repeated reopening caused by movement, rubbing, or pressure.

Hydration & nutrition

Stay hydrated and eat enough protein and calories to support tissue repair.

Avoid nicotine

Do not smoke—nicotine restricts blood flow and delays closure.

When to Seek Medical Care

A healthcare provider should evaluate a wound that remains open after several weeks, shows signs of infection, reopens repeatedly, becomes more painful, or drains heavily. Early care often means simple adjustments (dressing changes, pressure reduction, or treating infection) rather than hospitalization.

Key Takeaways

  • A wound that will not close often has an underlying barrier to healing.
  • Healing and closing are related, but not the same.
  • Infection, tissue damage, and moisture imbalance commonly delay closure.
  • Open wounds carry higher infection risk.
  • Early care improves outcomes and reduces complications.
Stephanie Wright, RN, BSN

About the Author

Stephanie Wright, RN, BSN

Stephanie Wright is a registered nurse and health writer with over 15 years of experience spanning bedside care, managed care, utilization review, and population health. With a background in communications, she specializes in translating clinical evidence into clear, patient-centered health information.

Her work focuses on chronic disease management, prescription medications, preventive care, and healthcare navigation—helping readers understand their options and feel confident advocating for their care.